76 entries « 1 of 2 »

2020

TC, Hitzeman; Y, Xie; RH, Zadikany; AP, Nikolova; R, Baum; B, Xu; S, Agvanian; GY, Melmed; DT, McGovern; DR, Geft; DH, Chang; JD, Moriguchi; A, Hage; B, Azarbal; LS, Czer; MM, Kittleson; JK, Patel; AHB, Wu; JA, Kobashigawa; M, Hamilton; TT, Hong; RM., Shaw

cBIN1 Score (CS) identifies ambulatory HFrEF patients and predicts cardiovascular events Journal Article

In: Front Physiology, 11 (503), 2020.

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Xiao, S; D, Shimura; R, Baum; DM, Hernandez; S, Agvanian; Y, Nagaoka; M, Katsumata; PD, Lampe; AG, Kleber; T, Hong; RM., Shaw

Auxiliary Trafficking Subunit GJA1-20k Protects Connexin43 from Degradation and Limits Ventricular Arrhythmias Journal Article

In: JCI, 2020.

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Y, Liu; K, Zhou; J, Li; S, Agvanian; A, Caldaruse; S, Shaw; TC, Hitzeman; RM, Shaw; TT., Hong

In Mice Subjected to Chronic Stress, Exogenous cBIN1 Preserves Calcium Handling Machinery and Cardiac Function Journal Article

In: JACC, 2020.

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I, Epifantseva; S, Xiao; RE, Baum; AG, Kleber; T, Hong; RM, Shaw

An Alternatively Translated Connexin 43 Isoform, GJA1-11k, Localizes to the Nucleus and Can Inhibit Cell Cycle Progression Journal Article

In: Biomolecules, 10 (3), 2020.

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2019

RM, Shaw; JE, Saffitz

A role for connexin-43 in Duchenne muscular dystrophy cardiomyopathy Journal Article

In: J. Clin. Invest., 130 (4), pp. 1608–1610, 2019.

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RM, Shaw

Correlating Cardiac Origin Neurohormonal Stress Levels With Heart Failure Outcomes Journal Article

In: JAMA Cardiol, 2019.

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AP, Nikolova; T, Hong; RM, Shaw

Letter by Nikolova et al Regarding Article, ‘Heart failure with preserved ejection fraction in perspective Journal Article

In: Circ. Res., 125 (4), pp. e24-e25, 2019.

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RH, Zadikany; T, Hong; RM, Shaw

Heart failure: distinguishing failing myocardium from volume overload Journal Article

In: Biomark Med, 13 (9), pp. 697–700, 2019.

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T, Hong; RM, Shaw

Editorial commentary: Extracellular vesicles in cardiovascular diagnosis and therapy Journal Article

In: Trends Cardiovasc. Med., 29 (6), pp. 324–325, 2019.

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2018

RM, Shaw; AP, Nikolova

The Clinical Course of a Genetic Dilated Cardiomyopathy: Letting the Cat Out of the BAG3 Journal Article

In: J. Am. Coll. Cardiol., 72 (20), pp. 2482–2484, 2018.

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Hitzeman TC Nikolova AP, Baum R

Association of a Novel Diagnostic Biomarker, the Plasma Cardiac Bridging Integrator 1 Score, With Heart Failure With Preserved Ejection Fraction and Cardiovascular Hospitalization Journal Article

In: JAMA Cardiol, 3 (12), pp. 1206–1210, 2018.

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Fu Y Basheer WA, Shimura D

Stress response protein GJA1-20k promotes mitochondrial biogenesis, metabolic quiescence, and cardioprotection against ischemia/reperfusion injury Journal Article

In: JCI Insight, 3 (20), 2018.

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Nikolova AP, Shaw RM

Editorial commentary: Are cytokines ready for prime time? Insights from markers and trials Journal Article

In: Trends Cardiovasc. Med., 28 (6), pp. 380–381, 2018.

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RM, Shaw; AP, Nikolova

A Surprising Noncanonical Role for Calcineurin in Pressure-Induced Cardiac Hypertrophy Journal Article

In: J. Am. Coll. Cardiol., 71 (6), pp. 668–669, 2018.

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Epifantseva I, Shaw RM

Intracellular trafficking pathways of Cx43 gap junction channels Journal Article

In: Biochim Biophys Acta Biomembr, 1860 (1), pp. 40–47, 2018.

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2017

Zhang SS Fu Y, Xiao S

Cx43 Isoform GJA1-20k Promotes Microtubule Dependent Mitochondrial Transport Journal Article

In: Front Physiol, 8 , pp. 905, 2017.

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Xiao S Basheer WA, Epifantseva I

GJA1-20k Arranges Actin to Guide Cx43 Delivery to Cardiac Intercalated Discs Journal Article

In: Circ. Res., 121 (9), pp. 1069–1080, 2017.

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Fu Y Xu B, Liu Y

The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles Journal Article

In: PLoS Biol., 15 (8), pp. e2002354, 2017.

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Y, Fu; RM, Shaw

CASAAV Technology to Examine Regulators of Heart Failure: Cause or Effect Journal Article

In: Circ. Res., 120 (12), pp. 1846–1848, 2017.

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Hong T, Shaw RM

Cardiac T-Tubule Microanatomy and Function Journal Article

In: Physiol. Rev., 97 (1), pp. 227–252, 2017.

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2016

WA, Basheer; RM, Shaw

The ‘Tail’ of Connexin43: An Unexpected Journey from Alternative Translation to Trafficking Journal Article

In: Biochimica et Biophysica Acta, 1863 (1848-56), 2016.

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T, Hong; RM, Shaw

Ion Channel Trafficking Journal Article

In: Ion Channels in Health and Disease, 2016.

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RM, Shaw

Ion Channel Trafficking in the Heart Book Chapter

In: 7/E , 2016.

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Manning JR Levitan BM, Withers CN

Rad-deletion Phenocopies Tonic Sympathetic Stimulation of the Heart Journal Article

In: J Cardiovasc Transl Res, 9 (5-6), pp. 432–444, 2016.

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Basheer WA, Shaw RM

Cx43 and CaV1.2 Ion Channel Trafficking in Healthy and Diseased Myocardium Journal Article

In: Circ Arrhythm Electrophysiol, 9 (6), pp. e001357, 2016.

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2015

Xiao S, Shaw RM

Cardiomyocyte protein trafficking: Relevance to heart disease and opportunities for therapeutic intervention Journal Article

In: Trends Cardiovasc. Med., 25 (5), pp. 379–389, 2015.

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Shaw RM Chen-Izu Y, Pitt GS

Na+ channel function, regulation, structure, trafficking and sequestration Journal Article

In: J. Physiol. (Lond.), 593 (6), pp. 1347–1360, 2015.

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Xiao S Fu Y, Hong TT

Cytoskeleton regulation of ion channels Journal Article

In: Circulation, 131 (8), pp. 689–691, 2015.

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2014

RM, Shaw

Desmosomal hotspots, microtubule delivery, and cardiac arrhythmogenesis Journal Article

In: Dev. Cell, 31 (2), pp. 139–140, 2014.

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Hong SG Zhang SS, Kléber AG; RM, Shaw

A micropatterning approach for imaging dynamic Cx43 trafficking to cell-cell borders Journal Article

In: FEBS Lett., 588 (8), pp. 1439–1445, 2014.

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Yang H Hong T, Zhang S

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia Journal Article

In: Nat. Med., 20 (6), pp. 624–632, 2014.

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Zhang SS Smyth JW, Sanchez JM

A 14-3-3 mode-1 binding motif initiates gap junction internalization during acute cardiac ischemia Journal Article

In: Traffic, 15 (6), pp. 684–699, 2014.

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Vesely ED Schumacher-Bass SM, Zhang L

Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes Journal Article

In: Circ. Res., 114 (6), pp. 982–992, 2014.

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SS, Zhang; RM, Shaw

Trafficking highways to the intercalated disc: new insights unlocking the specificity of connexin 43 localization Journal Article

In: Cell Commun. Adhes., 21 (1), pp. 43–54, 2014.

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2013

Ferrer T Samson SC, Jou CJ

3-OST-7 regulates BMP-dependent cardiac contraction Journal Article

In: PLoS Biol., 11 (12), pp. e1001727, 2013.

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JW, Smyth; RM, Shaw

Autoregulation of connexin43 gap junction formation by internally translated isoforms Journal Article

In: Cell Rep, 5 (3), pp. 611–618, 2013.

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RM, Shaw; HM, Colecraft

L-type calcium channel targeting and local signalling in cardiac myocytes Journal Article

In: Cardiovasc. Res., 98 (2), pp. 177–186, 2013.

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R, Cogswell; D, McGlothlin; E, Kobashigawa; R, Shaw; T., De Marco

Performance of the REVEAL model in WHO Group 2 to 5 pulmonary hypertension: application beyond pulmonary arterial hypertension. Journal Article

In: J Heart Lung Transplant, 32 (293-8), 2013.

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SS, Zhang; RM, Shaw

Multilayered regulation of cardiac ion channels Journal Article

In: Biochim Biophys Acta, 1833 (876-85), 2013.

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JR, Martens; RM, Shaw

Ion Channel Trafficking Book Chapter

In: 2013.

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RM, Shaw

Reduced sodium channels in human ARVC Journal Article

In: Heart Rhythm, 10 (3), pp. 420–421, 2013.

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Zhang L Gao D, Dhillon R

Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart Journal Article

In: PLoS ONE, 8 (4), pp. e60967, 2013.

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2012

Cogswell R Hong TT, James CA; RM, Shaw

Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy Journal Article

In: Heart Rhythm, 9 (6), pp. 961–967, 2012.

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Smyth JW Hong TT, Chu K; RM, Shaw

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes Journal Article

In: Heart Rhythm, 9 (5), pp. 812–820, 2012.

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LK, Svoboda; KG, Reddie; L, Zhang; ED, Vesely; ES, Williams; SM, Schumacher; RP, O'Connell; R, Shaw; SM, Day; JM, Anumonwo; KS, Carroll; JR., Martens

Redox-sensitive sulfenic acid modification regulates surface expression of the cardiovascular voltage-gated potassium channel Kv1.5. Journal Article

In: 2012.

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R, Cogswell; E, Kobashigawa; D, McGlothlin; R, Shaw; T., De Marco

Validation of the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL) pulmonary hypertension prediction model in a unique population and utility in the prediction of long-term survival.. Journal Article

In: 2012.

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Vogan J Smyth JW, Buch P

Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane Journal Article

In: Circ. Res., 110 (7), pp. 978–989, 2012.

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JW, Smyth; RM, Shaw

Visualizing cardiac ion channel trafficking pathways Journal Article

In: Meth. Enzymol., 505 , pp. 187–202, 2012.

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JW, Smyth; RM, Shaw

The gap junction life cycle Journal Article

In: Heart Rhythm, 9 (1), pp. 151–153, 2012.

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2011

Kim KH* Zhang SS*, Rosen A*

Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network Journal Article

In: Proc. Natl. Acad. Sci. U.S.A., 108 (33), pp. 13576–13581, 2011.

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76 entries « 1 of 2 »