76 entries « 1 of 2 »

2020

TC, Hitzeman; Y, Xie; RH, Zadikany; AP, Nikolova; R, Baum; B, Xu; S, Agvanian; GY, Melmed; DT, McGovern; DR, Geft; DH, Chang; JD, Moriguchi; A, Hage; B, Azarbal; LS, Czer; MM, Kittleson; JK, Patel; AHB, Wu; JA, Kobashigawa; M, Hamilton; TT, Hong; RM., Shaw

cBIN1 Score (CS) identifies ambulatory HFrEF patients and predicts cardiovascular events Journal Article

Front Physiology, 11 (503), 2020.

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Xiao, S; D, Shimura; R, Baum; DM, Hernandez; S, Agvanian; Y, Nagaoka; M, Katsumata; PD, Lampe; AG, Kleber; T, Hong; RM., Shaw

Auxiliary Trafficking Subunit GJA1-20k Protects Connexin43 from Degradation and Limits Ventricular Arrhythmias Journal Article

JCI, 2020.

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Y, Liu; K, Zhou; J, Li; S, Agvanian; A, Caldaruse; S, Shaw; TC, Hitzeman; RM, Shaw; TT., Hong

In Mice Subjected to Chronic Stress, Exogenous cBIN1 Preserves Calcium Handling Machinery and Cardiac Function Journal Article

JACC, 2020.

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I, Epifantseva; S, Xiao; RE, Baum; AG, Kleber; T, Hong; RM, Shaw

An Alternatively Translated Connexin 43 Isoform, GJA1-11k, Localizes to the Nucleus and Can Inhibit Cell Cycle Progression Journal Article

Biomolecules, 10 (3), 2020.

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2019

RM, Shaw; JE, Saffitz

A role for connexin-43 in Duchenne muscular dystrophy cardiomyopathy Journal Article

J. Clin. Invest., 130 (4), pp. 1608–1610, 2019.

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RM, Shaw

Correlating Cardiac Origin Neurohormonal Stress Levels With Heart Failure Outcomes Journal Article

JAMA Cardiol, 2019.

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AP, Nikolova; T, Hong; RM, Shaw

Letter by Nikolova et al Regarding Article, ‘Heart failure with preserved ejection fraction in perspective Journal Article

Circ. Res., 125 (4), pp. e24-e25, 2019.

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RH, Zadikany; T, Hong; RM, Shaw

Heart failure: distinguishing failing myocardium from volume overload Journal Article

Biomark Med, 13 (9), pp. 697–700, 2019.

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T, Hong; RM, Shaw

Editorial commentary: Extracellular vesicles in cardiovascular diagnosis and therapy Journal Article

Trends Cardiovasc. Med., 29 (6), pp. 324–325, 2019.

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2018

RM, Shaw; AP, Nikolova

The Clinical Course of a Genetic Dilated Cardiomyopathy: Letting the Cat Out of the BAG3 Journal Article

J. Am. Coll. Cardiol., 72 (20), pp. 2482–2484, 2018.

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Nikolova AP Hitzeman TC, Baum Caldaruse Agvanian Xie Geft DR Chang DH Moriguchi JD Hage Azarbal Czer LS Kittleson MM Patel JK Wu AHB Kobashigawa JA Hamilton Hong TT Shaw RM R A S Y A B M

Association of a Novel Diagnostic Biomarker, the Plasma Cardiac Bridging Integrator 1 Score, With Heart Failure With Preserved Ejection Fraction and Cardiovascular Hospitalization Journal Article

JAMA Cardiol, 3 (12), pp. 1206–1210, 2018.

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Basheer WA Fu Y, Shimura Xiao Agvanian Hernandez DM Hitzeman TC Hong TT Shaw RM D S S

Stress response protein GJA1-20k promotes mitochondrial biogenesis, metabolic quiescence, and cardioprotection against ischemia/reperfusion injury Journal Article

JCI Insight, 3 (20), 2018.

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Nikolova AP, Shaw RM

Editorial commentary: Are cytokines ready for prime time? Insights from markers and trials Journal Article

Trends Cardiovasc. Med., 28 (6), pp. 380–381, 2018.

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RM, Shaw; AP, Nikolova

A Surprising Noncanonical Role for Calcineurin in Pressure-Induced Cardiac Hypertrophy Journal Article

J. Am. Coll. Cardiol., 71 (6), pp. 668–669, 2018.

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Epifantseva I, Shaw RM

Intracellular trafficking pathways of Cx43 gap junction channels Journal Article

Biochim Biophys Acta Biomembr, 1860 (1), pp. 40–47, 2018.

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2017

Fu Y Zhang SS, Xiao Basheer WA Baum Epifantseva Hong TT Shaw RM S R I

Cx43 Isoform GJA1-20k Promotes Microtubule Dependent Mitochondrial Transport Journal Article

Front Physiol, 8 , pp. 905, 2017.

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Basheer WA Xiao S, Epifantseva Fu Kleber AG Hong TT Shaw RM I Y

GJA1-20k Arranges Actin to Guide Cx43 Delivery to Cardiac Intercalated Discs Journal Article

Circ. Res., 121 (9), pp. 1069–1080, 2017.

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Xu B Fu Y, Liu Agvanian Shaw RM Hong TT Y S

The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles Journal Article

PLoS Biol., 15 (8), pp. e2002354, 2017.

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Y, Fu; RM, Shaw

CASAAV Technology to Examine Regulators of Heart Failure: Cause or Effect Journal Article

Circ. Res., 120 (12), pp. 1846–1848, 2017.

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Hong T, Shaw RM

Cardiac T-Tubule Microanatomy and Function Journal Article

Physiol. Rev., 97 (1), pp. 227–252, 2017.

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2016

WA, Basheer; RM, Shaw

The ‘Tail’ of Connexin43: An Unexpected Journey from Alternative Translation to Trafficking Journal Article

Biochimica et Biophysica Acta, 1863 (1848-56), 2016.

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T, Hong; RM, Shaw

Ion Channel Trafficking Journal Article

Ion Channels in Health and Disease, 2016.

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RM, Shaw

Ion Channel Trafficking in the Heart Book Chapter

7/E , 2016.

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Levitan BM Manning JR, Withers CN Smith JD Shaw RM Andres DA Sorrell VL Satin J

Rad-deletion Phenocopies Tonic Sympathetic Stimulation of the Heart Journal Article

J Cardiovasc Transl Res, 9 (5-6), pp. 432–444, 2016.

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Basheer WA, Shaw RM

Cx43 and CaV1.2 Ion Channel Trafficking in Healthy and Diseased Myocardium Journal Article

Circ Arrhythm Electrophysiol, 9 (6), pp. e001357, 2016.

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2015

Xiao S, Shaw RM

Cardiomyocyte protein trafficking: Relevance to heart disease and opportunities for therapeutic intervention Journal Article

Trends Cardiovasc. Med., 25 (5), pp. 379–389, 2015.

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Chen-Izu Y Shaw RM, Pitt GS Yarov-Yarovoy Sack JT Maltsev VA Deschenes Mohler PJ Abriel Aldrich RW Cannell MB Catterall WA Chazin WJ Chiamvimonvat Grandi Hund TJ Izu LT Maier LS Marionneau Rajamani Rasmusson RL Sobie EA Belardinelli Clancy CE Bers DM V I H N E C S L

Na+ channel function, regulation, structure, trafficking and sequestration Journal Article

J. Physiol. (Lond.), 593 (6), pp. 1347–1360, 2015.

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Fu Y Xiao S, Hong TT Shaw RM

Cytoskeleton regulation of ion channels Journal Article

Circulation, 131 (8), pp. 689–691, 2015.

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2014

RM, Shaw

Desmosomal hotspots, microtubule delivery, and cardiac arrhythmogenesis Journal Article

Dev. Cell, 31 (2), pp. 139–140, 2014.

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Zhang SS Hong SG, Kléber AG Lee LP ; RM, Shaw

A micropatterning approach for imaging dynamic Cx43 trafficking to cell-cell borders Journal Article

FEBS Lett., 588 (8), pp. 1439–1445, 2014.

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Hong T Yang H, Zhang Cho HC Kalashnikova Sun Zhang Bhargava Grabe Olgin Gorelik Marbán Jan LY Shaw RM S M B H A M J J E

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia Journal Article

Nat. Med., 20 (6), pp. 624–632, 2014.

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Smyth JW Zhang SS, Sanchez JM Lamouille Vogan JM Hesketh GG Hong Tomaselli GF Shaw RM S T

A 14-3-3 mode-1 binding motif initiates gap junction internalization during acute cardiac ischemia Journal Article

Traffic, 15 (6), pp. 684–699, 2014.

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Schumacher-Bass SM Vesely ED, Zhang Ryland KE McEwen DP Chan PJ Frasier CR McIntyre JC Shaw RM Martens JR L

Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes Journal Article

Circ. Res., 114 (6), pp. 982–992, 2014.

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SS, Zhang; RM, Shaw

Trafficking highways to the intercalated disc: new insights unlocking the specificity of connexin 43 localization Journal Article

Cell Commun. Adhes., 21 (1), pp. 43–54, 2014.

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2013

Samson SC Ferrer T, Jou CJ Sachse FB Shankaran SS Shaw RM Chi NC Tristani-Firouzi Yost HJ M

3-OST-7 regulates BMP-dependent cardiac contraction Journal Article

PLoS Biol., 11 (12), pp. e1001727, 2013.

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JW, Smyth; RM, Shaw

Autoregulation of connexin43 gap junction formation by internally translated isoforms Journal Article

Cell Rep, 5 (3), pp. 611–618, 2013.

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RM, Shaw; HM, Colecraft

L-type calcium channel targeting and local signalling in cardiac myocytes Journal Article

Cardiovasc. Res., 98 (2), pp. 177–186, 2013.

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R, Cogswell; D, McGlothlin; E, Kobashigawa; R, Shaw; T., De Marco

Performance of the REVEAL model in WHO Group 2 to 5 pulmonary hypertension: application beyond pulmonary arterial hypertension. Journal Article

J Heart Lung Transplant, 32 (293-8), 2013.

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SS, Zhang; RM, Shaw

Multilayered regulation of cardiac ion channels Journal Article

Biochim Biophys Acta, 1833 (876-85), 2013.

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JR, Martens; RM, Shaw

Ion Channel Trafficking Book Chapter

2013.

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RM, Shaw

Reduced sodium channels in human ARVC Journal Article

Heart Rhythm, 10 (3), pp. 420–421, 2013.

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Gao D Zhang L, Dhillon Hong TT Shaw RM Zhu R J

Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart Journal Article

PLoS ONE, 8 (4), pp. e60967, 2013.

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2012

Hong TT Cogswell R, James CA Kang Pullinger CR Malloy MJ Kane JP Wojciak Calkins Scheinman MM Tseng ZH Ganz DeMarco Judge DP G J H P T; RM, Shaw

Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy Journal Article

Heart Rhythm, 9 (6), pp. 961–967, 2012.

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Hong TT Smyth JW, Chu Vogan Fong TS Jensen BC Fang Halushka MK Russell SD Colecraft Hoopes CW Ocorr Chi NC K J K H K; RM, Shaw

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes Journal Article

Heart Rhythm, 9 (5), pp. 812–820, 2012.

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LK, Svoboda; KG, Reddie; L, Zhang; ED, Vesely; ES, Williams; SM, Schumacher; RP, O'Connell; R, Shaw; SM, Day; JM, Anumonwo; KS, Carroll; JR., Martens

Redox-sensitive sulfenic acid modification regulates surface expression of the cardiovascular voltage-gated potassium channel Kv1.5. Journal Article

2012.

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R, Cogswell; E, Kobashigawa; D, McGlothlin; R, Shaw; T., De Marco

Validation of the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL) pulmonary hypertension prediction model in a unique population and utility in the prediction of long-term survival.. Journal Article

2012.

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Smyth JW Vogan J, Buch Zhang SS Fong Hong TT Shaw RM P T

Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane Journal Article

Circ. Res., 110 (7), pp. 978–989, 2012.

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JW, Smyth; RM, Shaw

Visualizing cardiac ion channel trafficking pathways Journal Article

Meth. Enzymol., 505 , pp. 187–202, 2012.

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JW, Smyth; RM, Shaw

The gap junction life cycle Journal Article

Heart Rhythm, 9 (1), pp. 151–153, 2012.

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2011

Zhang SS* Kim KH*, Rosen Smyth JW* Sakuma Delgado-Olguín Davis Chi NC Puviindran Gaborit Sukonnik Wylie JN Brand-Arzamendi Farman Kim Rose RA Marsden PA Zhu Zhou YQ Miquerol Henkelman RM Stainier DY Shaw RM Hui CC Bruneau BG Backx PH A* R* P M V N T K G J Y L

Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network Journal Article

Proc. Natl. Acad. Sci. U.S.A., 108 (33), pp. 13576–13581, 2011.

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76 entries « 1 of 2 »